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However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
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[DOI] [PubMed] [Google Scholar] 216.Sagar G, Sah RP, Javeed N, Dutta SK, Smyrk TC, Lau JS, et al
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