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For each of these parameters (TUNEL, Ki-67, COX-2, NF-ΞΊB and Trx-1), the number of positive cancer cells and the number of all (positive and negative) cancer cells were determined for each photograph by two pathologists blinded to their identity and the percentage of positive cells was calculated based on the average of the values generated by the two pathologists (maximal variation 4.2%)
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