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Many new questions about the mechanism of DNA methylation-mediated gene expression regulation in mammals have appeared: (i) what is the role of non-CG methylation in stem cells, in which it appears enriched on transcribed strands of gene bodies of highly active genes (Lister et al., 2009), and does it occur in different cell types as suggested in some studies
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In these models, algorithms are trained on a data set containing reference input and output data
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