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Collectively, these findings suggest that the integration of non-pharmacological strategies, such as HBOT, with pharmacological treatments may serve to optimize the therapeutic outcomes while potentially minimizing the dosage of medication required
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The role of SAC (10 −8 –10 −5 M) on tunicamycin-mediated cell death was investigated in PC12 cells and hippocampal neurons, showing a selective neuroprotective effect on the caspase-12-dependent apoptotic pathway [96, 100]
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